Ritonavir or lopinavir/ritonavir drastically boost plasma concentrations of oxycodone in nutritious human volunteers due to inhibition of CYP3A4 and CYP2D6.[fifty eight] Rifampicin considerably reduces plasma concentrations of oxycodone as a consequence of strong induction of CYP3A4.A vital A part of the assessment of the client with Long-term non-
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